Beginning early in multiple sclerosis (MS), smoldering neuroinflammation can be largely unseen and lead to disability accumulation.1,3 But there is hope.


The Unseen Pathway

Smoldering neuroinflammation: Thought to be a driver of disability accumulation3


Smoldering Neuroinflammation

The impact of disability accumulation on your patients


Addressing Both Pathways

You and the future of MS management

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  1. Cree BAC, Hollenbach JA, Bove R, et al; University of California, San Francisco MS-Epic Team. Silent progression in disease activity-free relapsing multiple sclerosis. Ann Neurol. 2019;85(5):653-666.
  2. Ziemssen T, Derfuss T, de Stefano N, et al. Optimizing treatment success in multiple sclerosis. J Neurol. 2016;263(6):1053-1065.
  3. Giovannoni G, Popescu V, Wuerfel J, et al. Smouldering multiple sclerosis: the ‘real MS’. Ther Adv Neurol Disord. 2022;15:17562864211066751. doi:10.1177/17562864211066751